Complex Regional Pain Syndrome (CRPS) Treatment in Atlanta, Marietta, and Fayetteville, GA

Complex Regional Pain Syndrome (CRPS) is a chronic pain condition that typically develops after an injury, surgery, or medical event. It is often marked by severe, persistent pain, along with changes in skin color, temperature, and sensitivity. At Regenerative Spine & Pain Specialists, our team provides compassionate, evidence-informed care for individuals living with CRPS in Atlanta, Marietta, and Fayetteville, GA.

Early evaluation and intervention may help reduce the severity of symptoms and preserve function. We offer personalized treatment plans that combine interventional, physical, and psychological strategies to support comprehensive recovery.

Complex Regional Pain Syndrome is a rare and often misunderstood pain disorder. It typically affects one limb—most commonly an arm or a leg—but can spread to other areas of the body. CRPS is thought to involve abnormal responses in the peripheral and central nervous systems following trauma or surgery.

There are two types:

  • CRPS-I: Occurs without confirmed nerve damage

  • CRPS-II: Occurs with confirmed nerve injury

Symptoms may include:

  • Continuous burning, throbbing, or aching pain

  • Sensitivity to touch or temperature (allodynia)

  • Skin color changes (red, blue, or pale)

  • Swelling and stiffness in the affected limb

  • Muscle weakness, tremors, or spasms

  • Decreased range of motion or coordination

  • Abnormal sweating or nail/hair growth in the area

Symptoms can fluctuate over time and may worsen without appropriate care.

Diagnosis is based on a detailed clinical evaluation that may include:

  • Medical and surgical history review

  • Physical and neurological exams

  • Imaging to rule out other conditions (e.g., bone scans, MRI)

  • Diagnostic nerve blocks to identify the source of pain

Because CRPS can mimic other conditions, evaluation by a pain specialist is important for accurate diagnosis.

Our treatment approach is multidisciplinary and may include:

  • Medications to address nerve sensitivity and inflammation

  • Physical therapy to improve function and prevent atrophy

  • Nerve blocks or sympathetic nerve injections

  • Spinal cord stimulation for patients with persistent or severe symptoms

  • Psychological support, including cognitive behavioral therapy, for those managing anxiety, depression, or trauma associated with chronic pain

Treatment is always customized to match the stage and severity of the condition.

Our experienced physicians—Dr. Zwade Marshall, and Dr. Jennifer Xiong—provide:

  • Board-certified interventional pain care

  • Advanced diagnostic tools for complex pain syndromes

  • Two convenient locations in Atlanta, Marietta, and Fayetteville, GA

We are committed to helping patients with CRPS find relief and improve their quality of life.